SC Manufacturing Conference & Expo 2025 – Dates, Agenda, and What to Expect

The South Carolina Manufacturing Conference & Expo 2025 is one of the largest manufacturing events in the Southeast United States. Scheduled for November 5–6, 2025 at the Greenville Convention Center in Greenville, South Carolina, the event brings together industry leaders, manufacturers, technology providers, and policymakers for two days of networking, education, and innovation.

Event Overview

• Dates: November 5–6, 2025
• Location: Greenville Convention Center, Greenville, SC
• Attendees: 1,400+ decision-makers, 150+ exhibiting companies
• Organizer: SC Biz News

The expo floor itself spans the size of three football fields, ensuring every participant passes through exhibitor booths on the way to conference sessions. This format creates maximum visibility for sponsors and strong engagement for attendees.

Keynote Speakers and Special Guests

• Joe Klecha, Chief Nuclear Officer at The Nuclear Company, will deliver insights on the intersection of energy and manufacturing strategy.
• Lt. Governor Pamela Evette joins the “Manufacturing Mavens” session, highlighting women leaders shaping South Carolina’s manufacturing future.
• Lou Kennedy, CEO of Nephron Pharmaceuticals, will headline the Manufacturing Mavens program, focusing on leadership and innovation.

Conference Agenda Highlights

Day 1 – November 5, 2025

• Autonomous Technology Panel – Explore advances in AGVs, mobile robots, autonomous forklifts, and drones. Featuring KION, Clemson University, USC, Oshkosh Defense, and SkyDrive.
• Palmetto Proud Luncheon & Awards – Unveiling SC-made products and honoring the state’s best manufacturing workplaces. Keynote by Cody Thacker of Scout Motors.
• AI in Manufacturing – How artificial intelligence is transforming production, asset management, and contextual data analysis. Panelists from Clemson, College of Charleston, Zeus Industrial.
• Sustainability & Circular Economy – Discussion on sustainable packaging, materials reuse, and circular manufacturing practices. Speakers from AFL, Sonoco, Sustain SC.

Day 2 – November 6, 2025

• Virtual Reality in Manufacturing – Practical uses of VR in safety training, design, and productivity.
• Manufacturing Mavens Program – Celebrating women leaders in South Carolina’s manufacturing ecosystem.

Expo Floor and Exhibitors

The Expo Hall showcases 150+ companies across automation, robotics, software, energy, workforce development, and advanced manufacturing technologies. The layout is designed to maximize exhibitor exposure, as attendees must walk the expo floor to access all sessions and luncheons.

Why Attend SC Manufacturing Conference & Expo 2025?

• Regional Focus, Global Relevance: While rooted in South Carolina, the conference covers hot global topics such as AI, autonomy, sustainability, and VR.
• Networking Opportunities: With leaders from manufacturing, academia, and government present, it’s the premier networking hub in the Southeast.
• Workforce & Policy Alignment: The event includes strong representation from education and state leadership, focusing on workforce development and future growth.
• Recognition & Awards: Programs like Palmetto Proud and Manufacturing Mavens celebrate innovation and leadership in the sector.

Quick Facts

• When is the SC Manufacturing Conference & Expo 2025? November 5–6, 2025, with more details on official website: SC Manufacturing Conference & Expo 2025
• Where is it held? Greenville Convention Center, Greenville, South Carolina.
• Who attends? Over 1,400 attendees including executives, engineers, policy leaders, and suppliers.
• What industries are covered? Automotive, aerospace, energy, industrial equipment, packaging, and more.

The SC Manufacturing Conference & Expo 2025 is more than a regional gathering – it’s a showcase of how manufacturing in South Carolina is embracing new technologies like AI, robotics, sustainability, and immersive training. With its combination of expo, high-profile speakers, and forward-looking panels, it has become a must-attend event for manufacturers in the Southeast and beyond.

If you want to stay ahead of manufacturing trends, connect with key players, and explore solutions shaping the future of production, make sure Greenville, SC, November 5–6, 2025 is on your calendar.

About MDCplus

Our key features are real-time machine monitoring for swift issue resolution, power consumption tracking to promote sustainability, computerized maintenance management to reduce downtime, and vibration diagnostics for predictive maintenance. MDCplus's solutions are tailored for diverse industries, including aerospace, automotive, precision machining, and heavy industry. By delivering actionable insights and fostering seamless integration, we empower manufacturers to boost Overall Equipment Effectiveness (OEE), reduce operational costs, and achieve sustainable growth along with future planning.